research topics in organometallic chemistry

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Organometallic chemistry articles from across Nature Portfolio

Organometallic chemistry is the study of the synthesis, structure and reactivity of chemical compounds that contain metal-carbon bonds. These compounds are often used as homogeneous catalysts.

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• Chemical bonding
• Cross-coupling reactions
• Metathesis reactions

Latest Research and Reviews

Analysis of chemical exchange in iridium N-heterocyclic carbene complexes using heteronuclear parahydrogen-enhanced NMR

Current efforts to enhance NMR signals using the signal amplification by reversible exchange (SABRE) focus on optimizing polarization transfer from parahydrogen-derived hydride ligands to the substrate, but this requires quantitative information on ligand exchange rates, which common NMR techniques struggle to provide. Here, the authors introduce an experimental spin order transfer sequence with readout occurring at hyperpolarization-enhanced 15 N nuclei that are directly interacting with the SABRE catalyst, enabling robust evaluation of ligand chemical exchange.

• Charbel D. Assaf
• Andrey N. Pravdivtsev

Reply to: An approach to the resolution of the dispute on collective atomic interactions

• Nuno A. G. Bandeira
• Ángel Martín Pendás
• Cina Foroutan-Nejad

Direct synthesis of α-functionalized amides via heteroatom–hydrogen insertion reactions using amide-sulfoxonium ylides

α-Functionalized Si-, Ge-, B-, Se-, and S- amide moieties are present in many medically active molecules, but their synthesis remains challenging. Here, the authors demonstrate a high-throughput synthesis using amide-sulfoxonium ylides as carbene precursors in a Si–H, Ge–H, B–H, Se–H, and S–H insertion reactions to target a wide range of α-silyl, α-geryl, α-boryl, α-selenyl, and α-sulfur (hetero)amides.

Alkali cation-π interactions in aqueous systems, modulating supramolecular stereoisomerism of nanoscopic metal-organic capsules

Contrary to common chemical intuition, cation-π interactions can persist in polar, aqueous reaction solutions, rather than in dry non-coordinative solvent systems. Here, the authors highlight how alkali ion-π interactions impart distinctive structure-influencing supramolecular forces that can be exploited in the preparation of nanoscopic metal-organic capsules.

• Swetanshu Tandon
• Wolfgang Schmitt

Simultaneous generation of residue-free reactive oxygen species and bacteria capture for efficient electrochemical water disinfection

Residue-free water disinfection is vital for safe drinking water. Here the authors develop an electrochemical system for microbial eradication by employing a dual-mode mechanism and a dynamic “live microbe capture–killing–dead microbe desorption” process for continuous and effective disinfection.

Synthesis and redox catalysis of Carbodiphosphorane ligated stannylene

Heavier group 14 carbene analogue display remarkable capability for small molecule activation but their application in redox catalysis remains elusive. Here, the authors report the synthesis and isolation of a stannylene with carbodiphosphorane ligand and characterize its catalytic activity in the hydrodefluorination reaction of fluoroarenes.

• Zhuchunguang Liu
• Zhijun Wang
• Zhaowen Dong

News and Comment

The Jekyll-and-Hyde electron transfer chemistry of hydrogen bonds

Hydrogen bonds get a bad rap in electronic materials because their weak, transient structure often results in poor performance. Now, this dogma has been turned on its head by intercalating molecules into two-dimensional superlattices to generate hydrogen-bonded organic–inorganic structures that feature significantly enhanced electrical conductivity.

• Peter J. Dahl
• Nikhil S. Malvankar

Triplet metallocarbenes featuring carbon-centred spin localization

Open-shell carbenes, which feature two unpaired electrons on a carbene carbon centre, are highly unstable compounds and are usually observed as excited-state species. Now, two triplet metallocarbenes have been stabilized by transition-metal and silyl substituents; the compounds have been characterized by various techniques including single-crystal X-ray diffraction, spectroscopy and quantum-chemical analyses.

A molecular sandwich with a lithium–aluminium filling

Compounds containing metal–metal bonds can provide fresh insights into electronic structure and bonding, and their synthesis can open up new chemical space. A sandwich complex containing a lithium–aluminium bond has now delivered some food for thought in this arena.

• David P. Mills

Polarizing the Be–Be bond

The Be–Be bond has long represented a ‘missing link’ between the H–H bond of dihydrogen and the B–B bond of diborane(4) species. Now, a complex with a polarized Be–Be bond that acts as a source of the beryllyl anion is reported. This work also reveals similarities between the homo-elemental linkages of boron and beryllium.

The synthesis behind the 2023 Nobel Prize

In 1993, a new route for the synthesis of semiconductor nanocrystals was reported that exploited organometallic chemistry to afford nearly monodisperse particles. 30 years later the award of the 2023 Nobel Prize in Chemistry can be directly traced to this single publication.

Catalytic reactions with low-valency ambiphilic gallium complexes

A one-pot method is introduced for synthesizing highly reactive and potentially chiral low-valency Ga( i ) complexes, facilitating their application as a versatile catalyst.

• Djamila Azrou
• Christophe Bour

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Activation of Unreactive Bonds and Organic Synthesis

• © 1999
• Shinji Murai 0 ,
• R. A. Gossage ,
• V. V. Grushin ,
• W. D. Jones ,
• F. Kakiuchi ,
• Y.-S. Lin ,
• Y. Mizobe ,
• M. Murakami ,
• T. G. Richmond ,
• M. Suginome ,
• A. Yamamoto

Department of Applied Chemistry Faculty of Engineering, Osaka University, Osaka

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• The first and only comprehensive overview of the explosive development in the field of bond activation, not only C-H but also other inert functionalities
• Directed to organic and inorganic chemists
• Presents new methodologies for bond cleavage and bond connection reactions that were previously infeasible offering tremendous new opportunites to do short, efficient organic syntheses in academia and industry
• Includes supplementary material: sn.pub/extras

Part of the book series: Topics in Organometallic Chemistry (TOPORGAN, volume 3)

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Transmetalation: a fundamental organometallic reaction critical to synthesis and catalysis

Halogen Bonds in Organic Synthesis and Organocatalysis

Homogeneous Catalysis with Organometallic Complexes of Group 2

• Anorganische Chemie
• Catalytic Reactions
• Inorganic Chemistry
• Metallorganische Chemie
• Organic Chemistry
• Organometallic Chemistry
• organische Chemie

Table of contents (10 chapters)

Front matter, a general survey and recent advances in the activation of unreactive chemical bonds by metal complexes.

• Robert A. Gossage, Gerard van Koten

Activation of C-H Bonds: Stoichiometric Reactions

• William D. Jones

Activation of C-H Bonds: Catalytic Reactions

• Fumitoshi Kakiuchi, Shinji Murai

Catalytic Activation of Methane and Ethane by Metal Compounds

• Ayusman Sen

Cleavage of Carbon—Carbon Single Bonds by Transition Metals

• Masahiro Murakami, Yoshihiko Ito

Activation of Si—Si Bonds by Transition-Metal Complexes

• Michinori Suginome, Yoshihiko Ito

Activation of C-O Bonds: Stoichiometric and Catalytic Reactions

• Yong-Shou Lin, Akio Yamamoto

Activation of Otherwise Unreactive C-Cl Bonds

• Vladimir V. Grushin, Howard Alper

Activation of the N-N Triple Bond in Molecular Nitrogen: Toward its Chemical Transformation into Organo-Nitrogen Compounds

• Masanobu Hidai, Yasushi Mizobe

Metal Reagents for Activation and Functionalization of Carbon-Fluorine Bonds

• Thomas G. Richmond

Back Matter

Editors and affiliations.

Shinji Murai

Bibliographic Information

Book Title : Activation of Unreactive Bonds and Organic Synthesis

Editors : Shinji Murai, H. Alper, R. A. Gossage, V. V. Grushin, M. Hidai, Y. Ito, W. D. Jones, F. Kakiuchi, G. Koten, Y.-S. Lin, Y. Mizobe, S. Murai, M. Murakami, T. G. Richmond, A. Sen, M. Suginome, … A. Yamamoto

Series Title : Topics in Organometallic Chemistry

DOI : https://doi.org/10.1007/3-540-68525-1

Publisher : Springer Berlin, Heidelberg

eBook Packages : Springer Book Archive

Copyright Information : Springer-Verlag Berlin Heidelberg 1999

Hardcover ISBN : 978-3-540-64862-8 Published: 16 April 1999

Softcover ISBN : 978-3-642-08436-2 Published: 17 September 2011

eBook ISBN : 978-3-540-68525-8 Published: 01 July 2003

Series ISSN : 1436-6002

Series E-ISSN : 1616-8534

Edition Number : 1

Number of Pages : IX, 267

Topics : Organic Chemistry , Inorganic Chemistry , Polymer Sciences

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Topics in Organometallic Chemistry

59 jahrgänge | 1998 - 2024.

Aims and Scope

The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics of pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience.

The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors. All chapters from Topics in Organometallic Chemistry are published Online First with an individual DOI. In references, Topics in Organometallic Chemistry is abbreviated as Top Organomet Chem and cited as a journal.

More information about this series is available at https://www.springer.com/series/3418

Alle Bücher der Reihe Topics in Organometallic Chemistry

2024 | Buch

Metallocenes in Regio- and Stereoselective Synthesis

This book presents the latest synthetic protocols for the assembly of functionalized Cp ligands and their transition metal complexes. Cyclopentadienyl (Cp) complexes of transition metals belong to the most important classes of transition metal …

Surface Functionalized Metal Catalysts

This book covers recent advances in the field of surface functionalized metal catalysts. It not only explores novel catalysts based on metal nanoparticles immobilized on functionalized supports, but also provides an overview of the latest …

2023 | Buch

Modes of Cooperative Effects in Dinuclear Complexes

This book presents recent advances in dinuclear complexes in which the metal-metal cooperative effect operates for obtaining substrate activation and high performance catalysts. Catalysis continues to be a fast expanding area to design efficient …

C-C Cross Couplings with 3d Base Metal Catalysts

This volume presents recent progress on 3d base metal catalyzed C-C cross coupling reactions. The contributions provide detailed discussions on the use of cheap metal catalysts such as Cr, Mn, Fe, Co, Ni, Cu, and Zn to construct Csp2-Csp2 …

Perspectives of Hydrosilylation Reactions

This volume describes the latest advances and perspectives in hydrosilylation, with a focus on new organometallic catalysts and their mechanistic aspects. Hydrosilylation is the reaction of ≡SiH with carbon-carbon, carbon-heteroatom or …

2021 | Buch

Iridium Catalysts for Organic Reactions

This new volume “Iridium Catalysts for Organic Reactions” in the series “Topics in Organometallic Chemistry” intends to update several representative well-known reactions and to introduce other less known or new reactions in particular covering …

Metal-Ligand Co-operativity

This book provides researchers in the fields of organic chemistry, organometallic chemistry and homogeneous catalysis with an overview of significant recent developments in the area of metal-ligand cooperativity, with a focus on pincer …

2020 | Buch

New Directions in the Modeling of Organometallic Reactions

This book focuses on the computational modeling of organometallic reactivity. In recent years, computational methods, particularly those based on Density Functional Theory (DFT) have been fully incorporated into the toolbox of organometallic …

Nanoparticles in Catalysis

This volume discusses the great potential of metal nanoparticle catalysts for complicated molecular synthesis and reviews the current progress of this field. The development of highly active and stable heterogeneous catalysts is a crucial subject …

2019 | Buch

Organometallics for Green Catalysis

This volume presents the latest developments in the use of organometallic catalysis for the formation of bulk chemicals and the production of energy, via green processes including efficient utilization of waste feedstocks from industry. The …

Organometallic Magnets

This volume highlights the recent advances and state of art in the experimental and theoretical studies of organometallic magnets. A plethora of organic ligands such as Mannich-base derivatives, redox-active chromophores, cyanides, Schiff base …

Organometallics in Process Chemistry

This volume gives an overview of the applications of organometallic chemistry in process chemistry relevant to the current topics in synthetic chemistry. This volume starts with an introduction on the historical development of organometallics in …

2018 | Buch

Rhodium Catalysis

The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of …

Chiral Lewis Acids

2016 | Buch

Carbon Dioxide and Organometallics

The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of or

The Privileged Pincer-Metal Platform: Coordination Chemistry & Applications

Organometallic flow chemistry, homo- and heterobimetallic complexes in catalysis, c-h bond activation and catalytic functionalization i, c-h bond activation and catalytic functionalization ii.

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Organometallic Chemistry

This is Prof. Hans Reich's collection of various topics on Organometallic Chemistry. Most of this content originated from his Chem 842 Course at the University of Wisconsin - Madison. Please choose a specific topic on the side menu for more detailed info.

Below is a general outline:

• Organometallic Chemistry - Introduction
• Methods for preparing organolithium reagents
• Li/H exchange, C-H acidities, kinetic and thermodynamic control, chelation
• Reduction of halides (Cl, Br, I) and sulfides (PhS) using Li or Li + ArH -
• Li/M exchange (M = Br, I, Sn, Hg, Se, Te)
• Shapiro reaction - tosylhydrazones and lithium reagents
• Addition of RLi to multiple bonds (C=O, C=C, CC)
• Structure and dynamics in solid and solution
• Aggregation - reactivity effects of donors
• structural effect on reactivity - delocalization, ion pair structure
• Stereochemistry of organolithium reagents
• Synthetic applications of organolithium reagents
• Organocopper Chemistry
• Organozinc Chemistry
• Asymmetric synthesis using Zn and Cu reagents
• Comparison of C, Si, Ge and Sn
• Preparation of organosilicon compounds and reagents
• Electrophilic and nucleophilic cleavage of C-Si bonds (Peterson, Brook)
• Preparation and uses of tin reagents (R 3 SnH, R 3 SnLi, R 3 SnSnR 3 , etc)
• Formation of C-Sn bonds
• Electrophilic, nucleophilic and radical substitution of C-Sn bonds, stereochemistry
• Preparation of organoboranes
• Typical reactions of organoboranes
• Organoaluminum chemistry
• Organoindium chemistry
• Comparison of S/Se/Te
• Selenium reagents (PhSeX, PhSeSePh, PhSeM, etc)
• Selenoxide elimination
• Selenium electrophiles
• -Lithio sulfides and selenides
• General features
• The Wittig, Horner and related reactions
• The Halogens, and Others

Chemistry and Chemical Engineering : Organometallic chemistry

Organometallic chemistry: key resources for researchers, encyclopedias and major reference works, review series, foundational texts.

• CHEMnetBASE chemical databases online CHEMnetBASE is a collection of 11 cutting-edge interactive chemistry databases. One-stop searching allows users to perform searches on chemical terms on chemical structures simultaneously across all databases within CHEMnetBASE except for Polymers: A Properties Database. It is also possible to search individual resources within CHEMnetBASE.

• Gmelin Handbook of Inorganic and Organometallic Chemistry Publication Date: 1817-1998 The Gmelin Handbook of Inorganic and Organometallic Chemistry is a comprehensive treatise that provides a collection of data in the fields of inorganic, organometallic, and physical chemistry. Also included are the areas of physics, metallurgy, geochemistry, mineralogy, and crystallography. The original source of the data is referenced. The text also includes tables of numerical data, curves, and other graphic material, including diagrams of apparatus. There are three basic parts to Gmelin, the Main Series volumes, Supplements to the Main Series, and a New Supplement Series. The set is shelved by the element symbol — consult the molecular formula index to determine which volume a compound is in. Selected data from print Gmelin is available online via the Reaxys database.

• Science of synthesis Houben-Weyl methods of molecular transformations "Science of Synthesis (SoS) provides a critical review of synthetic methodology developed to-date in the fields of organic and organometallic chemistry. Features include: Selection of molecular transformations by world-renowned experts with elaboration on scope and limitations; Full-text descriptions of synthetic methods with practical experimental procedures immediately applicable in the lab; Community of over 1,000 experts involved in the review and updating of methods; Logical organization of the synthetic methods for each functional group; and Intuitive search functions to allow rapid lead generation and route optimization." (publisher's description)

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Book series

Book titles in this series

Organometallics in process chemistry.

• Thomas J. Colacot
• Vilvanathan Sivakumar
• Copyright: 2019

Available Renditions

Organometallic Magnets

• Vadapalli Chandrasekhar
• Fabrice Pointillart

Organometallics for Green Catalysis

• Pierre H. Dixneuf
• Jean-François Soulé

Chiral Lewis Acids

• Koichi Mikami
• Copyright: 2018

Rhodium Catalysis

• Carmen Claver

C-H Bond Activation and Catalytic Functionalization II

• Henri Doucet
• Copyright: 2016

Nitrogen Fixation

• Yoshiaki Nishibayashi
• Copyright: 2017

Homo- and Heterobimetallic Complexes in Catalysis

Cooperative Catalysis

• Philippe Kalck

Organometallic Flow Chemistry

• Timothy Noël

Progress in Enantioselective Cu(I)-catalyzed Formation of Stereogenic Centers

• Syuzanna R. Harutyunyan

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